Cell Line Engineer (Technician)
The Professorship of Genome Biology develops and uses next-generation genome editing and regulation technologies for fundamental biological discovery and to create potential therapies for human genetic diseases. We are seeking a Cell Line Engineer (100% time) to develop advanced human cell culture models as part of an international collaboration. The successful applicant will use genome editing and other technologies to create cells with new genetic backgrounds in order to test how these affect cellular phenotypes. The Cell Line Engineer will work as part of a diverse team that comprises other technicians, graduate students, postdoctoral researchers, and senior scientists.
We are part of the D-BIOL Institute of Molecular Health Sciences at the ETH Zurich Honggerberg campus. The laboratory works in a fast-moving field with global exposure, so applicants should be excited for a dynamic environment.
- CRISPR-Cas engineering of human cell lines (knockout and knockin)
- Lentiviral or transposon-mediated engineering of stable cell lines
- Isolating and characterizing successfully engineered clonal lines
- Assisting with genome-wide CRISPR-Cas screens
- Molecular biology, such as cloning or preparation of next-generation sequencing libraries
- Organization of engineered cell line distribution between three research sites
- Qualified laboratory experience in molecular and cellular biology, (e.g. B.Sc. degree or apprenticeship minimum)
- Experience with human cell culture
- Experience with basic molecular biology (e.g. cloning and PCR)
We look forward to receiving your online application including a CV and letter of interest, describing your background and why you are a strong candidate for the position. Other pertinent documents may also be uploaded. Please address your application to Mr. Michael Wobmann, Human Resources. Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.