Cell Line Engineer (Technician)

80%-100%, Zurich, permanent

The Professorship of Genome Biology develops and uses next-generation genome editing and regulation technologies for fundamental biological discovery and to create potential therapies for human genetic diseases. We are seeking a Cell Line Engineer (100% time) to develop advanced human cell culture models as part of an international collaboration. The successful applicant will use genome editing and other technologies to create cells with new genetic backgrounds in order to test how these affect cellular phenotypes. The Cell Line Engineer will work as part of a diverse team that comprises other technicians, graduate students, postdoctoral researchers, and senior scientists.

We are part of the D-BIOL Institute of Molecular Health Sciences at the ETH Zurich Honggerberg campus. The laboratory works in a fast-moving field with global exposure, so applicants should be excited for a dynamic environment.

Job description

  • CRISPR-Cas engineering of human cell lines (knockout and knockin)
  • Lentiviral or transposon-mediated engineering of stable cell lines
  • Isolating and characterizing successfully engineered clonal lines
  • Assisting with genome-wide CRISPR-Cas screens
  • Molecular biology, such as cloning or preparation of next-generation sequencing libraries
  • Organization of engineered cell line distribution between three research sites

Your profile

  • Qualified laboratory experience in molecular and cellular biology, (e.g. B.Sc. degree or apprenticeship minimum)
  • Experience with human cell culture
  • Experience with basic molecular biology (e.g. cloning and PCR)

ETH Zurich

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.
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We look forward to receiving your online application including a CV and letter of interest, describing your background and why you are a strong candidate for the position. Other pertinent documents may also be uploaded. Please address your application to Mr. Michael Wobmann, Human Resources. Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

For more information on the Professorship please see the Corn Group website http://cornlab.org and the Institute for Molecular Health Sciences http://www.mhs.biol.ethz.ch/

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